个人简介

郑明明，中共党员，博士、教授、博士生导师。长期从事食品合成生物学与食品酶工程领域的研究和教学工作，聚焦高性能细胞工厂和酶催化剂构建、绿色酶催化体系和酶反应器研发，功能油脂和蛋白产品创制等领域研究。主持国家重点研发计划、国家自然基金、湖北省重点研发等项目20多项；在“Engineering”，“Bioresource Technology”等期刊上发表论文150多篇，累计引用5000多次；授权中、美、加、澳等发明专利60多件，许可转让金额超千万元；获得国家科技进步二等奖、中国农科院青年创新奖、油料作物专业委员会首届青年创新奖、湖北省脱贫攻坚先进个人。入选国家万人计划科技创新领军人才、青年拔尖人才、杰出青年农业科学家和湖北省楚天英才创新团队首席。兼任中国农学会理事、美国油脂化学家协会（AOCS）中国区常务理事；《Food & Medicine Homology Resources》副主编，《Food Safety and Health》、《食品与生物技术学报》等期刊编委。

教育经历

2005-2010 武汉大学化学博士学位
2001-2005 郑州大学化学学士学位

工作经历

2010.06-2018.12，中国农科院油料所，助理研究员、副研究员
2016.09-2017.09，美国加州大学河滨分校，生物催化，访问学者
2019.01-，中国农科院油料所，研究员，博士生导师
2026.08-，华中农业大学，教授，博士生导师

研究领域

食品合成生物学与酶工程、油脂和蛋白生物合成与增效利用

科研项目

(1) 国家重点研发计划项目，功能性脂质生物合成与提质加工关键技术研究及应用，2025.10-2028.9
(2) 国家重点研发计划课题，功能性脂质分子修饰与改性关键技术研发与示范，2021.12-2026.11
(3) 国家自然科学基金面上项目，pH刺激响应型界面酶催化体系构建与脂质结构重组机制研究，2023.01-2026.12
(4) 国家自然科学基金面上项目，油脂连续流酶法脱酸与功能酯的同步生成机制研究，2020.01-2023.12

成果奖励

(1)郑明明(8/10); 油料功能脂质高效制备关键技术与产品创制，国务院, 国家科技进步二等奖，2016
(2)郑明明（1/15），功能性脂质生物合成与提质加工关键技术创新及应用，中国农科院，青年创新奖，2023
(3) 国家特支计划科技创新领军人才, 中共中央组织部，2022
(4) 国家特支计划青年拔尖人才, 中共中央组织部，2018
(5) 杰出青年农业科学家，农业农村部，2018
(6) 湖北省楚天英才创新团队首席科学家，湖北省委组织部、省科技厅，2023
【代表性论文】
[1] Zhouliang Sun, Yufei Zhang, Yi Zhang, Huanyu Zheng, Chen Yu, Kai Shan, Yang Li, Mingming Zheng*. Hybrid gels based on zein nanoparticles, pectin and hydroxypropyl guar gum co-stabilized MLCT-rich Pickering emulsion gels and beeswax oleogels for functional fat substitutes. Carbohydrate Polymers, 2026, 382, 125261.
[2] Qi Li, Ruiying Gao, Yi Zhang, Yufei Zhang, Tieliang Liu, Yu-Cai He*, Ming-Ming Zheng*. Enhanced upgrading of corncob to furfuryl alcohol with a novel silica-supported SO₄²⁻-TiO₂ chemocatalyst and immobilized whole-cell biocatalyst. Green Chemistry, 2023, 25, 7764–7773.
[3] Yufei Zhang, Yundong Lai, Mingming Zheng*. Ultrasound-assisted intensification of Pickering interfacial biocatalysis preparation of vitamin A aliphatic esters. Ultrasonics Sonochemistry, 2024, 107, 106929.
[4] Tiantian Zhang, Yi Zhang, Changyue Deng, Huaying Zhong, Tingting Gu, Kheng-Lim Goh, Zhongmu Han, Mingming Zheng*, Yibin Zhou. Green and efficient synthesis of highly liposoluble and antioxidant L-ascorbyl esters by immobilized lipases. Journal of Cleaner Production, 2022, 379, 134772.
[5] Zhouliang Sun, Yufei Zhang, Ji Zhang, Yi Zhang, Huanyu Zheng, Yang Li, Chen Yu, Mingming Zheng*. Tannic acid-crosslinked zein-lipase complex stabilized multichamber Pickering emulsion for efficient diacylglycerol production. Food Chemistry, 2026, 525, 150589.
[6] Shengli Ding, Mengqi Wang, Guiqing Lin, Yanrong Song, Ji Zhang, Yufei Zhang, Mingming Zheng*. Coral-inspired in situ immobilized lipase on covalent organic framework for efficient synthesis of flavor esters. Food Chemistry, 2026, 506, 148153.
[7] Chuang Yang, Yufei Zhang, Mingming Zheng*. Continuous-flow enzymatic reactor for medium- and long-chain triglycerides production: From process intensification to flavor retention. Food Chemistry, 2026, 507, 148184.
[8] Zhouliang Sun, Yufei Zhang, Huanyu Zheng, Yi Zhang, Yang Li, Mingming Zheng*. Preparation of phytosterol esters based on food-grade Pickering emulsion stabilized by lipase-adsorbed zein-hydroxypropyl chitosan nanoparticles. Food Chemistry, 2025, 493, 145734.
[9] Huihui Liu, Yihan Liu, Zhongmu Han, Yufei Zhang*, Mingming Zheng*. Enhanced Pickering interfacial biocatalysis in phosphatidylserine synthesis via phospholipase D immobilization with optimized bifunctional strategy. Food Chemistry, 2025, 492, 145393.
[10] Run Liu, Yi Zhang*, Yuanzhi Xu, Zhonghui Liu, Jinhang Chen, Kheng-Lim Goh, Yufei Zhang, Mingming Zheng*. Molecular docking simulation reveals the lipase-substrate binding mechanism in the enzymatic synthesis of diacylglycerol-enriched vegetable oils. Food Chemistry, 2025, 474, 143236.
[11] Chuang Yang, Yufei Zhang, Yuanzhi Xu, Yibin Zhou, Shiyi Li, Mingming Zheng*. Broadly adapted and efficient enzymatic transesterification production of medium and long-chain triglycerides via coconut oil and long-chain triacylglycerols. Food Chemistry, 2025, 469, 142499.
[12] Liumei Wu, Dongming Li, Fuyang Bi, Chao Yu, Yufei Zhang, Mingming Zheng*. Highly efficient enzymatic enrichment of n-3 polyunsaturated fatty acid glycerides via interfacial biocatalysis in Pickering emulsions. Food Chemistry, 2025, 470, 142683.
[13] Huanyu Zheng, Ji Zhang, Zhouliang Sun, Mengqi Wang, Yufei Zhang*, Mingming Zheng*. pH-Tunable gliadin–chitosan–lipase ternary complexes enabling efficient interfacial synthesis of phytosterol ester. Food Research International, 2026, 226, 118159.
[14] Yufei Zhang, Jing Jin, Daoxue Zhou, Huihui Liu, Jinmei Lu, Mingming Zheng*. PVP-assisted in situ immobilizing lipase on covalent organic framework for enhanced catalytic activity and stability in bioconversions. International Journal of Biological Macromolecules, 2024, 283, 137856.
[15] Xuefeng Li, Jun Wei, Yufei Zhang*, Yuanzhi Xu, Wenlong Yuan, Lin Mei, Shengjiao Yu, Mingming Zheng*. Hollow Double-Layered Mesoporous Silica as an Enzyme Immobilization Platform: Enhancing Biocatalytic Efficiency in Docosahexaenoic Acid Phosphatidylcholine. ACS Applied Materials & Interfaces, 2025, 17, 54437.
【排名第一发明专利】
[1] 一种酶法连续制备中长链甘油三酯的方法，ZL202610083330.4.
[2] 一种基于磷脂酶微马达反应器的油脂脱胶方法，ZL202511431526.X.
[3] 一种富含甘油二酯的健康食用油制备方法及其产品，ZL202411091710.X.
[4] 一种碳基微通道反应器及其制备方法与应用，ZL202410305178.0.
[5] 一种OPL/OPO/LPL比例可控的母乳替代脂的制备方法及其产品,ZL202210895481.1.
[6] 一种油脂酶法脱酸与功能脂质同步制备的方法，ZL202210276861.7.
[7] 一种固定化酶皮克林乳液酶反应体系及其应用，ZL201910105333.3.
[8] 醋酸纤维素整体柱及其酶反应器及制备方法、应用，ZL201810838478.X.
[9] 中空介孔纳米碳球固定化酶及其制备方法，ZL201711274729.8.
[10] 一种高效制备酚酸甘油酯的方,ZL201610737228.8.

其它

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